Aloe-emodin exhibits growth-suppressive effects on androgen-independent human prostate cancer DU145 cells via inhibiting the Wnt/β-catenin signaling pathway: an in vitro and in silico study

• Κύριοι συγγραφείς: Talib Hussain (Συγγραφέας), Ahmed Alafnan (Συγγραφέας), Ibrahim Abdullah Almazni (Συγγραφέας), Nawal Helmi (Συγγραφέας), Afrasim Moin (Συγγραφέας), Hanadi M. Baeissa (Συγγραφέας), Amir Mahgoub Awadelkareem (Συγγραφέας), AbdElmoneim O. Elkhalifa (Συγγραφέας), Tahani Bakhsh (Συγγραφέας), Abdulrahman Alzahrani (Συγγραφέας), Rashed Mohammed Alghamdi (Συγγραφέας), Mohammad Khalid (Συγγραφέας), Rohit Kumar Tiwari (Συγγραφέας), Syed Mohd Danish Rizvi (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

At the molecular level, several developmental signaling pathways, such as Wnt/β-catenin, have been associated with the initiation and subsequent progression of prostate carcinomas. The present report elucidated the anti-cancerous attributes of an anthraquinone, aloe-emodin (AE), against androgen-ind...