D-mannose attenuates bone loss in mice Treg cell proliferation and gut microbiota-dependent anti-inflammatory effects

• Main Authors: Hao Liu (Author), Ranli Gu (Author), Yuan Zhu (Author), Xiaomin Lian (Author), Siyi Wang (Author), Xuenan Liu (Author), Zhang Ping (Author), Yunsong Liu (Author), Yongsheng Zhou (Author)
• Format: Book
• Published: SAGE Publishing, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: D-mannose exhibits strong anti-inflammatory properties, but whether it has beneficial effects on preventing and treating osteoporosis remains unknown. Methods: Female, 12-month-old senile C57BL6/J mice (s-Man group) and 8-week-old ovariectomized C57BL6/J mice (OVX-Man group) were treated...