New Benzimidazothiazolone Derivatives as Tyrosinase Inhibitors with Potential Anti-Melanogenesis and Reactive Oxygen Species Scavenging Activities

• Main Authors: Hee Jin Jung (Author), Dong Chan Choi (Author), Sang Gyun Noh (Author), Heejeong Choi (Author), Inkyu Choi (Author), Il Young Ryu (Author), Hae Young Chung (Author), Hyung Ryong Moon (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Thirteen (<i>Z</i>)-2-(substituted benzylidene)benzimidazothiazolone analogs were synthesized and evaluated for their inhibitory activity against mushroom tyrosinase. Among the compounds synthesized, compounds <b>1</b>-<b>3</b> showed greater inhibitory activity t...