Immunomodulatory drug methotrexate used to treat patients with chronic inflammatory rheumatisms post-chikungunya does not impair the synovial antiviral and bone repair responses.

• Main Authors: Yosra Bedoui (Author), Claude Giry (Author), Marie-Christine (Author), Jimmy Selambarom (Author), Pascale Guiraud (Author), Philippe Gasque (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chikungunya virus (CHIKV) is a mosquito-transmitted RNA alphavirus causing major outbreaks of infectious chronic inflammatory rheumatisms (CIR). Recently, methotrexate (MTX), a disease modifying anti-rheumatic drug has been used successfully to treat patients suffering from rheumatoid-like arthritis...