Slc6a13 Deficiency Attenuates Pasteurella multocida Infection-Induced Inflammation via Glycine-Inflammasome Signaling

• Hlavní autoři: Fang He (Autor), Yangyang Qiu (Autor), Xiaoyan Wu (Autor), Yaoyao Xia (Autor), Liu Yang (Autor), Chenlu Wu (Autor), Pan Li (Autor), Rui Zhang (Autor), Rendong Fang (Autor), Nengzhang Li (Autor), Yuanyi Peng (Autor)
• Médium: Kniha
• Vydáno: Karger Publishers, 2022-07-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

We have previously demonstrated that Slc6a13-deficient (Slc6a13−/−; KO) mice are resistant to P. multocida infection, which might be in connection with macrophage-mediated inflammation; however, the specific metabolic mechanism is still enigmatic. Here we reproduce the less sensitive to P. multocida...