Bone-derived MSCs encapsulated in alginate hydrogel prevent collagen-induced arthritis in mice through the activation of adenosine A2A/2B receptors in tolerogenic dendritic cells

• Main Authors: Gaona Shi (Author), Yu Zhou (Author), Wenshuai Liu (Author), Chengjuan Chen (Author), Yazi Wei (Author), Xinlong Yan (Author), Lei Wu (Author), Weiwei Wang (Author), Lan Sun (Author), Tiantai Zhang (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tolerogenic dendritic cells (tolDCs) facilitate the suppression of autoimmune responses by differentiating regulatory T cells (Treg). The dysfunction of immunotolerance results in the development of autoimmune diseases, such as rheumatoid arthritis (RA). As multipotent progenitor cells, mesenchymal...