Regulation of KV channel voltage-dependent activation by transmembrane β subunits

• Main Authors: Xiaohui eSun (Author), Mark A. eZaydman (Author), Jianmin eCui (Author)
• Format: Book
• Published: Frontiers Media S.A., 2012-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Voltage-activated K+ (KV) channels are important for shaping action potentials and maintaining resting membrane potential in excitable cells. KV channels contain a central pore-gate domain (PGD) surrounded by four voltage-sensing domains (VSD). The VSDs will change conformation in response to altera...