Indole-3-propionic acid alleviates sepsis-associated acute liver injury by activating pregnane X receptor

• Main Authors: Shuang Wang (Author), Liangzhi Xiong (Author), Zhihua Ruan (Author), Xiaofang Gong (Author), Yanrong Luo (Author), Chengyi Wu (Author), Yu Wang (Author), Hui Shang (Author), Jingyi Chen (Author)
• Format: Book
• Published: BMC, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The morbidity and mortality of sepsis are extremely high, which is a major problem plaguing human health. However, current drugs and measures for the prevention and treatment of sepsis have little effect. Sepsis-associated acute liver injury (SALI) is an independent risk factor f...