Potential Therapeutic Functions of PU-91 and Quercetin in Personalized Cybrids Derived from Patients with Age-Related Macular Degeneration, Keratoconus, and Glaucoma

• Main Authors: Nasim Salimiaghdam (Author), Lata Singh (Author), Mithalesh Kumar Singh (Author), Marilyn Chwa (Author), Shari Atilano (Author), Zahra Mohtashami (Author), Anthony Nesburn (Author), Baruch D. Kuppermann (Author), M. Cristina Kenney (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study is to investigate the therapeutic potential of higher doses of PU-91, quercetin, or in combination on transmitochondrial cybrid cell lines with various mtDNA haplogroups derived from patients with age-related macular degeneration (AMD), glaucoma (Glc), keratoconus (KC), and nor...