Change of CGRP Plasma Concentrations in Migraine after Discontinuation of CGRP-(Receptor) Monoclonal Antibodies

• Main Authors: Bianca Raffaelli (Author), Maria Terhart (Author), Mira Pauline Fitzek (Author), Kristin Sophie Lange (Author), Jasper Mecklenburg (Author), Lucas Hendrik Overeem (Author), Anke Siebert (Author), Elisabeth Storch (Author), Uwe Reuter (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Discontinuation of treatment with monoclonal antibodies (mAb) targeting the Calcitonin Gene-Related Peptide (CGRP) pathway leads to an increase in migraine frequency. We aimed to assess changes in free and total CGRP plasma concentrations after the discontinuation of CGRP(-receptor) mAbs. This prosp...