Open label smoking cessation with varenicline is associated with decreased glutamate levels and functional changes in anterior cingulate cortex: preliminary findings

• المؤلفون الرئيسيون: Muriah Dawn Wheelock (مؤلف), Meredith A Reid (مؤلف), Harrison eTo (مؤلف), David eWhite (مؤلف), Karen L Cropsey (مؤلف), Adrienne Carol Lahti (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2014-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Rationale: Varenicline, the most effective single agent for smoking cessation, is a partial agonist at α4β2 nicotinic acetylcholine receptors. Increasing evidence implicates glutamate in the pathophysiology of addiction and one of the benefits of treatment for smoking cessation is the ability to reg...