Semi-Mechanism-Based Pharmacokinetic-Toxicodynamic Model of Oxaliplatin-Induced Acute and Chronic Neuropathy

Oxaliplatin (L-OHP) is widely prescribed for treating gastroenterological cancer. L-OHP-induced peripheral neuropathy is a critical toxic effect that limits the dosage of L-OHP. An ideal chemotherapeutic strategy that does not result in severe peripheral neuropathy but confers high anticancer effica...

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Main Authors: Shinji Kobuchi (Author), Risa Shimizu (Author), Yukako Ito (Author)
Format: Book
Published: MDPI AG, 2020-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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