Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6‐hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots

Abstract The suitability of the endogenous 6‐hydroxymelatonin/melatonin urinary metabolic ratio as a surrogate for the paraxanthine/caffeine ratio to predict cytochrome P450 1A2 (CYP1A2) activity was assessed in this study. Twelve healthy volunteers completed four study sessions spread over 1 month...

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Main Authors: Gaëlle Magliocco (Author), Jules Desmeules (Author), Caroline Flora Samer (Author), Aurélien Thomas (Author), Youssef Daali (Author)
Format: Book
Published: Wiley, 2022-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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