Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6‐hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots
Abstract The suitability of the endogenous 6‐hydroxymelatonin/melatonin urinary metabolic ratio as a surrogate for the paraxanthine/caffeine ratio to predict cytochrome P450 1A2 (CYP1A2) activity was assessed in this study. Twelve healthy volunteers completed four study sessions spread over 1 month...
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Main Authors: | Gaëlle Magliocco (Author), Jules Desmeules (Author), Caroline Flora Samer (Author), Aurélien Thomas (Author), Youssef Daali (Author) |
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Format: | Book |
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Wiley,
2022-06-01T00:00:00Z.
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