Genome-wide analysis of aberrant methylation of enhancer DNA in human osteoarthritis

• Main Authors: Xiaozong Lin (Author), Li Li (Author), Xiaojuan Liu (Author), Jun Tian (Author), Weizhuo Zheng (Author), Jin Li (Author), Limei Wang (Author)
• Format: Book
• Published: BMC, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Osteoarthritis is a chronic musculoskeletal disease characterized by age-related gradual thinning and a high risk in females. Recent studies have shown that DNA methylation plays important roles in osteoarthritis. However, the genome-wide pattern of methylation in enhancers in os...