Microdeletion on chromosome 8p23.1 in a familial form of severe Buruli ulcer.

• Main Authors: Quentin B Vincent (Author), Aziz Belkadi (Author), Cindy Fayard (Author), Estelle Marion (Author), Ambroise Adeye (Author), Marie-Françoise Ardant (Author), Christian R Johnson (Author), Didier Agossadou (Author), Lazaro Lorenzo (Author), Julien Guergnon (Author), Christine Bole-Feysot (Author), Jeremy Manry (Author), Patrick Nitschké (Author), Ioannis Theodorou (Author), Jean-Laurent Casanova (Author), Laurent Marsollier (Author), Annick Chauty (Author), Laurent Abel (Author), Alexandre Alcaïs (Author), Franco-Beninese Buruli Research Group (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Buruli ulcer (BU), the third most frequent mycobacteriosis worldwide, is a neglected tropical disease caused by Mycobacterium ulcerans. We report the clinical description and extensive genetic analysis of a consanguineous family from Benin comprising two cases of unusually severe non-ulcerative BU....