The Thiazide-Sensitive Co-Transporter Promotes the Development of Sodium Retention in Mice with Diet-Induced Obesity

• Main Authors: Matthew R P Davies (Author), Kurt Gleich (Author), Marina Katerelos (Author), Mardiana Lee (Author), Peter F Mount (Author), David A Power (Author)
• Format: Book
• Published: Karger Publishers, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Intravascular volume expansion due to sodium retention is involved in the pathogenesis of obesity-related hypertension. Institution of high fat diet (HFD) feeding leads to an initial state of positive sodium balance due to enhanced tubular reabsorption of sodium, but which tubular s...