Oral Bisphenol A Worsens Liver Immune-Metabolic and Mitochondrial Dysfunction Induced by High-Fat Diet in Adult Mice: Cross-Talk between Oxidative Stress and Inflammasome Pathway

• Main Authors: Claudio Pirozzi (Author), Adriano Lama (Author), Chiara Annunziata (Author), Gina Cavaliere (Author), Clara Ruiz-Fernandez (Author), Anna Monnolo (Author), Federica Comella (Author), Oreste Gualillo (Author), Mariano Stornaiuolo (Author), Maria Pina Mollica (Author), Giuseppina Mattace Raso (Author), Maria Carmela Ferrante (Author), Rosaria Meli (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lines of evidence have shown the embryogenic and transgenerational impact of bisphenol A (BPA), an endocrine-disrupting chemical, on immune-metabolic alterations, inflammation, and oxidative stress, while BPA toxic effects in adult obese mice are still overlooked. Here, we evaluate BPA's worsen...