MiR-205 Regulates LRRK2 Expression in Dopamine Neurons in Parkinson's Disease through Methylation Modification

• Main Authors: Hongwei Wang (Author), Jie Li (Author), Liang Tao (Author), Luting Lv (Author), Jinghui Sun (Author), Tengteng Zhang (Author), Huimin Wang (Author), Jiandong Wang (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: We explored the methylation modification in miR-205 promoter during the pathological changes of Parkinson's disease (PD) and its regulation on Leucine-Rich Repeat Kinase 2 (LRRK2), clarified the important role of methylation in miR-205 promoter region in PD, explained the role of mi...