Histopathological and biomedical parameters determination in the protective effect of crocin on hepatotoxicity induced by methotrexate in rats

• Main Authors: Cyrus Jalili (Author), Amir Abdolmaleki (Author), Shiva Roshankhah (Author), Mohammad Reza Salahshoor (Author)
• Format: Book
• Published: Shahrekord University of Medical Sciences, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Methotrexate (Met) as a chemotherapy drug has many side effects, such as infiltration of neutrophils and the development of oxidative stress. Crocin (Cro), a carotenoid isolated from saffron, has numerous therapeutic characteristics including anticancer and antioxidant activities. This...