Prevention of bleomycin-induced pulmonary fibrosis by vaccination with the Tocilizumab mimotope

• 主要な著者: Jin Guo (著者), Lin Yang (著者), Haoming Song (著者), Li Bai (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

ABSTRACTMimotope, a kind of peptide vaccine, is developed to bind natural receptor and inhibit the downstream signaling. We have demonstrated that the vaccination of Tocilizumab mimotopes could alleviate the renal fibrosis by interfering with both IL-6 and ferroptosis signaling. However, the effect...