Prevention of bleomycin-induced pulmonary fibrosis by vaccination with the Tocilizumab mimotope

• Egile Nagusiak: Jin Guo (Egilea), Lin Yang (Egilea), Haoming Song (Egilea), Li Bai (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

ABSTRACTMimotope, a kind of peptide vaccine, is developed to bind natural receptor and inhibit the downstream signaling. We have demonstrated that the vaccination of Tocilizumab mimotopes could alleviate the renal fibrosis by interfering with both IL-6 and ferroptosis signaling. However, the effect...