Poly ε-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model

• Main Authors: Ekta Singh (Author), Riyaz Ali M. Osmani (Author), Rinti Banerjee (Author), Amr Selim Abu Lila (Author), Afrasim Moin (Author), Khaled Almansour (Author), Hany H. Arab (Author), Hadil Faris Alotaibi (Author), El-Sayed Khafagy (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder with synovitis and articular pathology as its primary expositions. Leflunomide (Lfd) is an anti-rheumatic drug that is effective in the treatment of RA, but displays severe side effects upon prolonged systemic administration. Lo...