Personalized Piperacillin Dosing for the Critically Ill: A Retrospective Analysis of Clinical Experience with Dosing Software and Therapeutic Drug Monitoring to Optimize Antimicrobial Dosing

• Main Authors: Ute Chiriac (Author), Daniel C. Richter (Author), Otto R. Frey (Author), Anka C. Röhr (Author), Sophia Helbig (Author), Judit Preisenberger (Author), Stefan Hagel (Author), Jason A. Roberts (Author), Markus A. Weigand (Author), Alexander Brinkmann (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Optimization of antibiotic dosing is a treatment intervention that is likely to improve outcomes in severe infections. The aim of this retrospective study was to describe the therapeutic exposure of steady state piperacillin concentrations (c_PIP) and clinical outcome in critic...