Carbon tetrachloride-induced acute liver toxicity: selecting dosage and biomarkers for evaluating hepatoprotective drugs in ICR outbred mice

• Main Authors: Theerut Luangmonkong (Author), Chanitkarn Pransin (Author), Ladawan Nopphalee (Author), Sirada Meechai (Author), Suprawee Chunya (Author), Atis Rattanavaraha (Author), Naphat Kaewnoppharat (Author), Thayida Khuituan (Author), Sanpetch Bunyakiat (Author), Warisara Parichatikanond (Author)
• Format: Book
• Published: Faculty of Pharmacy, Mahidol University, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Evaluating effects of putative chemical or herbal agents against a single intraperitoneal administration of carbon tetrachloride (CCl4) in rodents is a widely used model for studying hepatoprotective potency. Since the toxic effects of CCl4 is dependent on individual species; therefore, our study ai...