Platelet thromboxane inhibition by low‐dose aspirin in polycythemia vera: Ex vivo and in vivo measurements and in silico simulation

• Main Authors: Giovanna Petrucci (Author), Alberto Giaretta (Author), Paola Ranalli (Author), Viviana Cavalca (Author), Alfredo Dragani (Author), Benedetta Porro (Author), Duaa Hatem (Author), Aida Habib (Author), Elena Tremoli (Author), Carlo Patrono (Author), Bianca Rocca (Author)
• Format: Book
• Published: Wiley, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Low‐dose aspirin is currently recommended for patients with polycythemia vera (PV), a myeloproliferative neoplasm with increased risk of arterial and venous thromboses. Based on aspirin pharmacodynamics in essential thrombocythemia, a twice‐daily regimen is recommended for patients with PV...