Panax notoginseng saponins reverse P-gp-mediated steroid resistance in lupus: involvement in the suppression of the SIRT1/FoxO1/MDR1 signalling pathway in lymphocytes

Abstract Background P-glycoprotein (P-gp)-mediated steroid resistance (SR) has been suggested to play a significant role in lupus nephritis (LN) treatment failure. Panax notoginseng saponins (PNS), the main effective components of the traditional Chinese medicine notoginseng, exhibited potent revers...

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Main Authors: Feng Pan (Author), Yue-jin Li (Author), Ying Lu (Author)
Format: Book
Published: BMC, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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