Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway

• Main Authors: Qian Zeng (Author), Yuyang Luo (Author), Xiaoxue Sang (Author), Minlin Liao (Author), Binbin Wen (Author), Zhengang Hu (Author), Mei Sun (Author), Ziqiang Luo (Author), Xiaoting Huang (Author), Wei Liu (Author), Siyuan Tang (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis is a fatal interstitial lung disease for which effective drug therapies are lacking. Senegenin, an effective active compound from the traditional Chinese herb <i>Polygala tenuifolia Willd</i>, has been shown to have a wide range of pharmacological effects. I...