One extraction tool for in vitro-in vivo extrapolation? SPME-based metabolomics of in vitro 2D, 3D, and in vivo mouse melanoma models

• Autors principals: Karol Jaroch (Autor), Paulina Taczyńska (Autor), Marta Czechowska (Autor), Joanna Bogusiewicz (Autor), Kamil Łuczykowski (Autor), Katarzyna Burlikowska (Autor), Barbara Bojko (Autor)
• Format: Llibre
• Publicat: Elsevier, 2021-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Solid phase microextraction (SPME) in combination with high-resolution mass spectrometry was employed for the determination of metabolomic profile of mouse melanoma growth within in vitro 2D, in vitro 3D, and in vivo models. Such multi-model approach had never been investigated before. Due to the lo...