β-hydroxybutyrate resensitizes colorectal cancer cells to oxaliplatin by suppressing H3K79 methylation in vitro and in vivo

Abstract Background Ketone β-hydroxybutyrate (BHB) has been reported to prevent tumor cell proliferation and improve drug resistance. However, the effectiveness of BHB in oxaliplatin (Oxa)-resistant colorectal cancer (CRC) and the underlying mechanism still require further proof. Methods CRC-Oxa-res...

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Main Authors: Meng Deng (Author), Peijie Yan (Author), Hui Gong (Author), Guiqiu Li (Author), Jianjie Wang (Author)
Format: Book
Published: BMC, 2024-06-01T00:00:00Z.
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