Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals

• Main Authors: Catarina Marques (Author), Cristina Mega (Author), Andreia Gonçalves (Author), Paulo Rodrigues-Santos (Author), Edite Teixeira-Lemos (Author), Frederico Teixeira (Author), Carlos Fontes-Ribeiro (Author), Flávio Reis (Author), Rosa Fernandes (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP-IV) inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model of type 2 diabetes mellitus; the Zucker diabetic fatty (ZDF) rat: 20-week-old rats were treated with sitagliptin...