Therapeutic Drug Monitoring of Busulfan in Patients Undergoing Hematopoietic Cell Transplantation: A Pilot Single-Center Study in Taiwan

• Main Authors: Rong-Long Chen (Author), Li-Hua Fang (Author), Xin-Yi Yang (Author), Mohsin El Amrani (Author), Esther Veronique Uijtendaal (Author), Yen-Fu Chen (Author), Wei-Chi Ku (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Busulfan has been used as a conditioning regimen in allogeneic hematopoietic cell stem transplantation (HSCT). Owing to a large inter-individual variation in pharmacokinetics, therapeutic drug monitoring (TDM)-guided busulfan dosing is necessary to reduce graft failure and relapse rate. As there exi...