Impact of Cuminaldehyde and Indomethacin Co-Administration on Inflammatory Responses in MIA-Induced Osteoarthritis in Rats

• Main Authors: Sebastião Vieira de Morais (Author), Gustavo Pereira Calado (Author), Rafael Cardoso Carvalho (Author), João Batista Santos Garcia (Author), Thyago Moreira de Queiroz (Author), Antonio José Cantanhede Filho (Author), Alberto Jorge Oliveira Lopes (Author), Maria do Socorro de Sousa Cartágenes (Author), Gerson Ricardo de Souza Domingues (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) remains a chronic incurable condition, presenting substantial challenges in treatment. This study explores a novel strategy by investigating the concurrent use of cuminaldehyde, a natural compound, with indomethacin in animal models of MIA-induced OA. Our results demonstrate that...