Cell-penetrating peptide-conjugated copper complexes for redox-mediated anticancer therapy

• Main Authors: Quim Peña (Author), Sergi Rodríguez-Calado (Author), A. Jalila Simaan (Author), Mercè Capdevila (Author), Pau Bayón (Author), Oscar Palacios (Author), Julia Lorenzo (Author), Olga Iranzo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metal-based chemotherapeutics like cisplatin are widely employed in cancer treatment. In the last years, the design of redox-active (transition) metal complexes, such as of copper (Cu), has attracted high interest as alternatives to overcome platinum-induced side-effects. However, several challenges...