Oxaliplatin Enhances the Apoptotic Effect of Mesenchymal Stem Cells, Delivering Soluble TRAIL in Chemoresistant Colorectal Cancer

• Main Authors: Adriana G Quiroz-Reyes (Author), Paulina Delgado-González (Author), José F. Islas (Author), Adolfo Soto-Domínguez (Author), Carlos A. González-Villarreal (Author), Gerardo R. Padilla-Rivas (Author), Elsa N. Garza-Treviño (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A key problem in colorectal cancer (CRC) is the development of resistance to current therapies due to the presence of cancer stem cells (CSC), which leads to poor prognosis. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a protein that activates apoptosis in cancer cells through...