Congenital Hypothyroidism Patients With Thyroid Hormone Receptor Variants Are Not Rare: A Systematic Review

• Main Authors: Dong-Zhu Da MM (Author), Ye Wang MD, PhD (Author), Min Wang MD, PhD (Author), Zhi Long MM (Author), Qian Wang MD, PhD (Author), Jun Liu MD, PhD (Author)
• פורמט: ספר
• יצא לאור: SAGE Publishing, 2021-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Background Primary congenital hypothyroidism (CH) is a common endocrine and metabolic disease. Various genetic factors, including the thyroid hormone receptor (TSHR), play an important role in CH. Aim To explore the occurrence of pathogenic TSHR variants in CH. Methods We searched published articles...