SDF-1α Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia

• Main Authors: Zhe Chen (Author), Shufen Zhou (Author), Jianyun Li (Author), Hui Li (Author), Can Huang (Author), Qin Guo (Author), Tiantian Zhang (Author), Bingya Yang (Author), Chuanqing Tu (Author), Chengshan Guo (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

B cells play a central role in the pathogenesis of immune thrombocytopenia (ITP) by participating in humoral immunity. Meanwhile, regulatory B cells (Bregs), one subset of B cells, express negative regulatory effect on ITP. Mesenchymal stem cells (MSCs) have been demonstrated in the ability to induc...