Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135)

• Main Authors: Sabrina Jones (Author), Azure L. Yarbrough (Author), William E. Fantegrossi (Author), Paul L. Prather (Author), John M. Bush (Author), Anna Radominska‐Pandya (Author), Ryoichi Fujiwara (Author)
• Format: Book
• Published: Wiley, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Synthetic cannabinoids (SCBs), designer drugs marketed as legal alternatives to marijuana, act as ligands to cannabinoid receptors; however, they have increased binding affinity and potency, resulting in toxicity symptoms such as cardiovascular incidents, seizures, and potentially death. N‐...