Insects in anthelminthics research: Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni.

• Main Authors: Josina Kellershohn (Author), Laura Thomas (Author), Steffen R Hahnel (Author), Arnold Grünweller (Author), Roland K Hartmann (Author), Martin Hardt (Author), Andreas Vilcinskas (Author), Christoph G Grevelding (Author), Simone Haeberlein (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Natural products have moved into the spotlight as possible sources for new drugs in the treatment of helminth infections including schistosomiasis. Surprisingly, insect-derived compounds have largely been neglected so far in the search for novel anthelminthics, despite the generally recognized high...