Near‐infrared‐induced drug release from antibody-drug double conjugates exerts a cytotoxic photo‐bystander effect

• Hoofdauteurs: Kazuomi Takahashi (Auteur), Hirotoshi Yasui (Auteur), Shunichi Taki (Auteur), Misae Shimizu (Auteur), Chiaki Koike (Auteur), Kentaro Taki (Auteur), Hiroshi Yukawa (Auteur), Yoshinobu Baba (Auteur), Hisataka Kobayashi (Auteur), Kazuhide Sato (Auteur)
• Formaat: Boek
• Gepubliceerd in: Wiley, 2022-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Ideal cancer treatments specifically target and eradicate tumor cells without affecting healthy cells. Therefore, antibody‐based therapies that specifically target cancer antigens can be considered ideal cancer therapies. Antibodies linked with small‐molecule drugs (i.e., antibody-drug conj...