Hydroxychloroquine Does Not Function as a Direct Zinc Ionophore

• Main Authors: Oisín N. Kavanagh (Author), Shayon Bhattacharya (Author), Luke Marchetti (Author), Robert Elmes (Author), Finbarr O'Sullivan (Author), John P. Farragher (Author), Shane Robinson (Author), Damien Thompson (Author), Gavin M. Walker (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug-mediated correction of abnormal biological zinc homeostasis could provide new routes to treating neurodegeneration, cancer, and viral infections. Designing therapeutics to facilitate zinc transport intracellularly is hampered by inadequate concentrations of endogenous zinc, which is often prote...