Aerosol exposure to Rift Valley fever virus causes earlier and more severe neuropathology in the murine model, which has important implications for therapeutic development.

• Main Authors: Christopher Reed (Author), Kenny Lin (Author), Catherine Wilhelmsen (Author), Brian Friedrich (Author), Aysegul Nalca (Author), Ashley Keeney (Author), Ginger Donnelly (Author), Joshua Shamblin (Author), Lisa E Hensley (Author), Gene Olinger (Author), Darci R Smith (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rift Valley fever virus (RVFV) is an important mosquito-borne veterinary and human pathogen that can cause severe disease including acute-onset hepatitis, delayed-onset encephalitis, retinitis and blindness, or a hemorrhagic syndrome. Currently, no licensed vaccine or therapeutics exist to treat thi...