Development of a small cell lung cancer organoid model to study cellular interactions and survival after chemotherapy

• Main Authors: Chandani Sen (Author), Caroline R. Koloff (Author), Souvik Kundu (Author), Dan C. Wilkinson (Author), Juliette M. Yang (Author), David W. Shia (Author), Luisa K. Meneses (Author), Tammy M. Rickabaugh (Author), Brigitte N. Gomperts (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Small-cell-lung-cancer (SCLC) has the worst prognosis of all lung cancers because of a high incidence of relapse after therapy. While lung cancer is the second most common malignancy in the US, only about 10% of cases of lung cancer are SCLC, therefore, it is categorized as a rare and...