Genetic Association of UGT1A1 Promoter Variants (c.-3279T>G and c.-3156G>A) with Neonatal Hyperbili-rubinemia in an Iranian Population

• Main Authors: Nasim Pouralizadeh (Author), Gholamali Mamouri (Author), Abbas Boskabadi (Author), Hassan Boskabadi (Author), Houshang Rafatpanah (Author), Ali Moradi (Author), Hassan Mehrad-Majd (Author)
• Format: Book
• Published: Mashhad University of Medical Sciences, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Several studies have reported that two promoter variants (c.-3279T>G and c.-3156G>A) in UDP-glucuronosyltransferase (UGT1A1) gene may contribute to neonatal hyperbilirubinemia. However, these variants have not been investigated in Iranian neonates. This cross-sectional study aimed...