The Possible Cardio-Protective Effects of Ethanolic Artichoke Extract against 5- Fluorouracil Induced Cardiac Toxicity in Rats

• Main Authors: Intesar T. Numan (Author), Maha N. Hamad (Author), Ammar A. Fadhil (Author), Safa M. Najim (Author)
• Format: Bog
• Udgivet: College of Pharmacy University of Baghdad, 2017-03-01T00:00:00Z.
• Fag: article
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Cardiac toxicity can occur during the therapy with several cytotoxic drugs, including 5- Fluorouracil (5- FU). It is an antimetabolite that acts during the S phase of the cell cycle and is activated by thymidine phosphorylase into fluorodeoxyuridylate (5 fluoro 2'deoxyuridine 5'monophospha...