Potential utility of targeted Nanopore sequencing for improving etiologic diagnosis of bacterial and fungal respiratory infection

• Main Authors: Wai Sing Chan (Author), Chun Hang Au (Author), Sau Man Leung (Author), Dona N. Ho (Author), Elaine Yue Ling Wong (Author), Man Yan To (Author), Man Kin Ng (Author), Tsun Leung Chan (Author), Edmond Shiu Kwan Ma (Author), Bone Siu Fai Tang (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Diversified etiology of lower respiratory tract infection renders diagnosis challenging. The mainstay microbial culture is time-consuming and constrained by variable growth requirements. In this study, we explored the use of Nanopore sequencing as a supplementary tool to alleviat...