Are mast cells instrumental for fibrotic diseases?

• Main Authors: Catherine eOvered-Sayer (Author), Laura eRapley (Author), Tomas eMustelin (Author), Deborah Lee Clarke (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disorder of unknown etiology characterised by accumulation of lung fibroblasts and extracellular matrix deposition, ultimately leading to compromised tissue architecture and lung function capacity. IPF has a heterogeneous clinical course; however t...