Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic Regulation

• Main Authors: Muthu Thiruvengadam (Author), Baskar Venkidasamy (Author), Umadevi Subramanian (Author), Ramkumar Samynathan (Author), Mohammad Ali Shariati (Author), Maksim Rebezov (Author), Shabari Girish (Author), Sivakumar Thangavel (Author), Anand Raj Dhanapal (Author), Natalya Fedoseeva (Author), Joohyun Lee (Author), Ill-Min Chung (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress is a pathological condition occurring due to an imbalance between the oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 (NRF2), encoded by the gene <i>NFE2L2</i>, is the master regulator of phase II antioxidant enzymes that protect...