Sirtuin 3 in renal diseases and aging: From mechanisms to potential therapies

• Main Authors: Xuan Peng (Author), Haiqiang Ni (Author), Baicheng Kuang (Author), Zhiheng Wang (Author), Shuaiheng Hou (Author), Shiqi Gu (Author), Nianqiao Gong (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The longevity protein sirtuins (SIRTs) belong to a family of nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases. In mammals, SIRTs comprise seven members (SIRT1-7) which are localized to different subcellular compartments. As the most prominent mitochondrial deacetylases, SIRT3 is known...