Natural Lipid Extracts as an Artificial Membrane for Drug Permeability Assay: In Vitro and In Silico Characterization

• Үндсэн зохиолчид: Anna Vincze (Зохиогч), Gergely Dékány (Зохиогч), Richárd Bicsak (Зохиогч), András Formanek (Зохиогч), Yves Moreau (Зохиогч), Gábor Koplányi (Зохиогч), Gergely Takács (Зохиогч), Gábor Katona (Зохиогч), Diána Balogh-Weiser (Зохиогч), Ádám Arany (Зохиогч), György T. Balogh (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

In vitro non-cellular permeability models such as the parallel artificial membrane permeability assay (PAMPA) are widely applied tools for early-phase drug candidate screening. In addition to the commonly used porcine brain polar lipid extract for modeling the blood-brain barrier's permeability...