Bioequivalence of Alendronate and Vitamin D3 in a Combination Tablet Versus Corresponding-Dose Individual Tablets in Healthy Taiwanese Volunteers, Determined Using a Novel Plasma Alendronate Assay

• Main Authors: D. Hamish Wright, PhD (Author), Ramon Mols, BSc (Author), Kevin R Brown, BA (Author), Geng-Chang Yeh, MD, PhD (Author), Eric Woolf, PhD (Author), Lisa Hickey, MS (Author), Stefan Zajic, PhD (Author)
• Format: Book
• Published: Elsevier, 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study was designed to demonstrate that alendronate (ALN)/vitamin D3 combination tablets (ALN/D5600) are bioequivalent to corresponding doses of ALN and vitamin D3 as individual tablets in healthy Taiwanese volunteers. Methods: In this open-label, randomized, 2-period, crossover study...